Top Supplements for Cholesterol Management

Omega-3 Fatty Acids (Fish Oil, Krill Oil, or Algal Oil)

  • How it helps: Lowers triglycerides significantly; may slightly raise HDL and reduce inflammation.

  • Dose: 1,000–4,000 mg/day of combined EPA + DHA (higher doses often prescription).

  • Notes: Best taken with meals containing fat for absorption. May thin blood (caution with anticoagulants).

Red Yeast Rice

  • How it helps: Contains monacolin K, chemically identical to lovastatin (a statin drug). Reduces LDL cholesterol and total cholesterol.

  • Dose: Commonly 600–1,200 mg twice daily.

  • Notes: Can cause the same side effects as statins (muscle pain, liver strain). Must be used with provider supervision.

Niacin (Vitamin B3)

  • How it helps: Increases HDL (“good cholesterol”), lowers LDL, triglycerides, and lipoprotein(a).

  • Dose: 1,000–2,000 mg/day (therapeutic levels).

  • Notes: Can cause flushing, liver toxicity, and blood sugar spikes — best under medical monitoring.

Plant Sterols & Stanols

  • Reduce cholesterol absorption in the intestines.

  • Found in fortified foods and supplements.

  • Clinical studies show they can reduce LDL by 10–15%.

Soluble Fiber (Psyllium, Glucomannan, Oats/Barley)

  • Helps bind cholesterol in the gut.

  • Regular intake lowers LDL and supports blood sugar balance.

  • Tip: Aim for 5–10 grams/day, with plenty of water.

Garlic Extract

  • May modestly reduce cholesterol.

  • Also supports blood pressure and vascular health.

  • Safe for most people but interacts with blood thinners.

Berberine

  • Herbal extract shown to lower LDL, triglycerides, and improve blood sugar.

  • Works on pathways similar to metformin.

  • Typical dose: 500 mg 2–3x daily with meals.

Coenzyme Q10 (CoQ10)

  • Doesn’t directly lower cholesterol but supports heart health and energy.

  • Helps reduce statin-related muscle pain.

  • Common dose: 100–200 mg/day.

Safety Disclaimer

Not all supplements are right for everyone. Some (like red yeast rice and niacin) can act like medications and require monitoring. Always discuss your supplement plan with a healthcare provider — especially if you are on prescription medications.

At The Green Leaf Clinic, we personalize your care plan with lab testing, supplement guidance, and lifestyle strategies tailored to your health goals.

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