Understanding C. diff: What You Need to Know
C. diff, short for Clostridioides difficile, is a type of bacteria that can cause serious infection in the colon. It is one of the most common healthcare-associated infections in the United States, and cases are also increasing in the community.
When the balance of good bacteria in the gut is disrupted — often after antibiotics — C. diff can multiply and release toxins that damage the lining of the intestine. The result can range from mild diarrhea to life-threatening colitis.
Symptoms of C. diff
Watery diarrhea (three or more times per day for at least 2 days)
Abdominal cramping or pain
Fever
Nausea or loss of appetite
Dehydration
In severe cases: bloody stools, severe abdominal pain, or rapid heart rate
How Do People Get C. diff?
C. diff spores can live on surfaces for months and are resistant to many disinfectants. Infection often occurs after:
Recent antibiotic use (the #1 risk factor)
Hospitalization or long-term care stays
Weakened immune system
Previous C. diff infection
Spores spread through contaminated hands, surfaces, or equipment — which is why hand-washing with soap and water (not just sanitizer) is critical.
Diagnosis and Treatment
A stool test confirms the infection. Treatment depends on severity but may include:
Stopping the antibiotic that triggered the imbalance (if possible)
Targeted antibiotics against C. diff, such as fidaxomicin or vancomycin
Probiotics may be considered to support healthy gut flora, though evidence is mixed
In severe or recurrent cases: fecal microbiota transplantation (FMT) has shown high success rates
Preventing C. diff
Use antibiotics only when necessary and as prescribed.
Wash hands thoroughly with soap and water.
Clean surfaces with disinfectants known to kill C. diff spores (such as bleach).
Support gut health with a balanced diet rich in fiber and fermented foods.
Functional Medicine Perspective
At The Green Leaf Clinic, we also focus on the bigger picture of gut health:
Restoring balance with nutrition and lifestyle changes
Strengthening the immune system
Preventing recurrences by addressing the root cause, not just the infection
Takeaway: C. diff is a serious infection, but prevention and early treatment are powerful tools. If you’ve had recent antibiotics or hospitalization and notice new diarrhea, don’t ignore it — reach out to a healthcare provider right away.
Want to learn more about protecting your gut health? Book a consultation with The Green Leaf Clinic today: www.thegreenleafclinic.com